Sheesh. (Slaps forehead.)

Is there no way for the filter to recognize when the forbidden word is not actually being used, but is actually just the innards of a larger, real word? Forgive the ignorance on my part about how these things work….

I do appreciate the explanation. It’ll probably take a while for me to get used to the notion that I have to type a coherent thought quickly and at the same time scan for hidden “secret” words contained therein. But I’ll try!

Persiflage @ 103

Hi Valley Girl!

I’d be really interested in what your colleague has to say about this possible treatment.

I used to work in geriatrics. For years there were no treatments for Alzheimers. Then the baby boomer generation hits middle age and Big Pharma realises the huge potential profit. Now there are some drugs that slow the pace of the disease. Most clinical trials that I”m aware of are for better Alzheimer-slowing drugs, not Alzheimer-curing drugs.

Big Pharma’s got to make it’s fortune. How else would Mrs Lieberman keep Joey in the style to which he is accustomed?

Persiflage, I despise Big Pharma’s corporate values: they are inimical to the values of medicine.

Despite Pig Pharma’s prpaganda, most of the intellectual work in the development of novel drugs is still done in academia. Pig Pharma exploits this intellectual work. GOP/Reagan greatly cut fundinng for basic science, but have not eliminated public funding for biomedical research.

Please share with us your knowledge of the basic mechanisms by which “Alzheimer curing” drugs ready for Phase I clinical trials operate.

After describing the mechanism(s), please also share with us the specific drugs which have been shown in animal models to be “Alzheimer-curing”.

You seem most certain of your conclusions about a matter of vital importance for millions of Americans and their families. Please, enlighten us regarding the factual basis for your assertions.

Citations will be most useful in standard Medline format, but any citations of peer-reviewed journals supporting your assertions will be most eagerly reviewed.

What is the basic mechanism for the Alzheimer curing drug? Oh yes – and what is the drug?

Simple questions – so what are the answers?

Hi KM,

I’m sorry if I misled you, there are no Alzheimer-curing drugs.

I haven’t worked in the field for about 5 years and my remarks were based on social discussions with the geriatrician for whom I worked. At the time we were using Donepizil, an anti-cholinesterase inhibitor which, despite its side-effects, did seem to slow the progress of the disease. I recall one lady whose MMSE before Donepizil was 15, after 8 months on the drug it shot up to 23, despite the fact that nobody claimed the drug could reverse damage.

There was lots of talk about Clioquinol as a potential treatment for slowing or stopping the disease in its tracks but, as I no longer work in the field, I’m not sure how that has fared in clinical trials.

I’ll contact my ex-boss and get some references from him and I’ll let you know when I’ve done further research, if you’re interested. (Don’t worry, I actually enjoy researching these things).

Seems just now my latest reply to Kevin got stuck in the filter. Can you rescue me again?

[And is this a topic which just can’t be discussed in detail without getting stuck in moderation? I hate having to annoy y’all — and would love to know what to do in future to avoid the whole problem, if you have any suggestions.]

EDIT: Once again, y’all are really fast! Thanks so much!

My question still stands — any suggestions for me on how to avoid getting stuck in the filter? Or is it just a mystery?

[Mod Note; no mystery, there is a common brand name drug inside the word that describes people who have specific training.]

To CCmask, many good wishes for a positive outcome for the bereaved Lady and you.

((((((((((Diane & Mom))))))))))

or, my preferred way:

)))))))))))Diane & Mom(((((((((((

(a bear hug)

And Mrs. K8: thank you very much for the important info. No addictive personality, not a druggie at all. I don’t think it’s all stoicism; I think she’s just trying to force herself to heal. Your kindness is very much appreciated.

Kevin –

Thanks for clarifying. If it’s a question of “forcing” herself to heal, please tell her that there is PLENTY of data that indicates healing is MUCH FASTER when pain is relieved. Pain actually hinders the healing process. It causes extra stressors on all of the body systems, causing stress hormones to be released which have a negative effect. Sleep is not as deep or rejuvenating. Muscles tense automatically, even out of awareness of the patient, restricting blood flow, etc. There are even more physiological effects which I can’t remember off the top of my head now. Study after study shows that people heal much more slowly after injuries or surgeries if they don’t have adequate pain control.

We just got in from taking the dog to the vet and other errands — and now must eat late this evening.
However, like the other question I was addressing, I do have links in my files to data which provide plenty of proof of that point (pain hindering speed of healing), which would require a little bit of digging. Once again, I’ll be happy to do that if you like.

Unfortunately I had to get myself really up to speed about the latest scientific knowledge concerning pain management. We had a complete jerk of a doctor who was telling me it was all “in my head” and I was in unbearable agony for a very long time. I know way more than I ever wanted to know about the topic — and finding a qualified pain management specialist gave me my life back. No addiction, no love of medication, in fact a steady regular decrease in medication levels over time. I know my situation is very different from your daughter’s, but during the course of research I learned how many misconceptions there are about pain management — and about how many medical professionals, doctors and nurses, still labor under many misapprehensions.

Doctors who specialize in pain management are undertaking an ongoing effort to educate their colleagues on what the truth really is. So many patients have needlessly suffered.

((((((((((Diane & Mom))))))))))

or, my preferred way:

)))))))))))Diane & Mom(((((((((((

(a bear hug)

And Mrs. K8: thank you very much for the important info. No addictive personality, not a druggie at all. I don’t think it’s all stoicism; I think she’s just trying to force herself to heal. Your kindness is very much appreciated.

New Moon in Capricorn
Thursday, January 18, 2007

http://www.astrowisdom.com/thisnewmoon.htm

(Give us something new to read while we wait. I find it comforting to know tonight is the New Moon, a fresh start for Jane)

This is a very good omen. We plant root crops in the waning moon, because that prospers things that grown below ground, and above-ground crops in the waxing moon. Cancer, I would think, is an underground-y sort of thing. OK, so it’s not scientific, but it is comforting.

First of all, there’s Jane. I lost my only sister to it a couple of years ago. Second, our company (40 Employees) lost our CEO the day after Christmas in a car wreck. Tonite, the widow secretly shows me a letter she received from the four managers running the plant saying that if they do not receive a $25,000 raise by Tuesday, they are walking out. Which would mean that all of us “others” would be out of a job.

ccmask,

Managers are less important to a company than the other 36 workers. By which I mean, they are more ‘generic’ so more easily replaced. Does your widow-owner-lady have a CPA and /or lawyer she can trust? Such a person can arrange rent-a-managers for interim times and help her get over this without being held to ransom. Managers are dime-a-dozen, thriving small companies not so much. If there are shareholders there should already be an audit firm in place that can help with this.